Clinical Biochemistry
Responsible teacher: assoc. prof. RNDr. Eva Uhlíková, PhD.
Contact person: eva.uhlikova@fmed.uniba.sk
Announcement
The teaching of Clinical Biochemistry in the academic year 2024/2025 will begin in the week from 23.09.2024 following the current schedule.
Lectures for Clinical Biochemistry for students in the General Medicine study branch will be online. The lectures will be made available via MS Teams, in a team to which all 4th-year students will have access.
Students who are not yet assigned to the team "MF_Clinical Biochemistry_2025-2024" can request to be added to this team at the following address: lucia.laubertovafmed.uniba.sk
Program of lectures
Programme of the subject: CLINICAL BIOCHEMISTRY Study branch: GENERAL MEDICINE – 4th year Medical faculty UK L E C T U R E S Winter semester – academic year 2024/2025 |
Date | Topic of the lecture | Lecturer |
1. | General clinical biochemistry – instruction, laboratory examination and its phases, pre-analytic, analytic and post-analytic phase. Diagnostic criteria of laboratory test. Reference values and evaluation of laboratory tests results. | doc. Uhlíková |
2. | Plasma proteins in diagnostics. Hyper- and hypoproteinaemia. Monoclonal gammopathies and their diagnosis. | doc. Uhlíková |
3. | Fundamentals of clinical enzymology. Examination of enzyme activities in diagnostics. | doc. Uhlíková |
4. | Lipid parameters in diagnostics. Hyperlipoproteinemia’s and their classification. Diagnosis of lipid metabolism disorders. | doc. Uhlíková |
5. | Laboratory tests in diabetology. Diagnosis and monitoring of a patient with diabetes mellitus. Diabetic complications. | doc. Uhlíková |
6. | Laboratory tests in gastroenterology. Gastric examination, examination of pancreatic function and small intestine resorption disorders. | doc. Uhlíková |
7. | Laboratory tests in hepatology. Examination of liver disorders and hepatic function. Cholestasis and its diagnosis. | doc. Uhlíková |
8. | Laboratory tests in nephrology. Urine examination – physical, chemical and microscopic. Examination of glomerular filtration and tubular function. | doc. Uhlíková |
9. | Laboratory tests in cardiology. Myocardial ischemia and diagnostics of acute myocardial infarction. Risk factors of atherosclerosis. | doc. Uhlíková |
10. | Laboratory tests in cancer patients. Tumour markers and their use in the diagnosis and monitoring of patients with oncological diseases. | doc. Uhlíková |
11. | Laboratory tests for some endocrinological diseases. Examination of thyroid function and function of adrenal cortex. | doc. Uhlíková |
12. | Acid-base balance disorders and their diagnostics. Acidosis, alkalosis and combined acid-base balance disorders. | doc. Uhlíková |
13. | Investigation of less common biological fluids – cerebrospinal fluid, synovial fluid and amniotic fluid. | doc. Uhlíková |
Reference values required for the test
parameter | values | parameter | values |
Hemoglobin | 135-175 g/L M 115-160 g/L F | Albumin | 35-53 g/L |
Hematocrit | 39-51% M 33-42% F | Urea in serum | 2.5-8.3 mmol/L |
Erythrocytes | 4.2-5.7x1012/L M 3.5-5.1x1012/L F | Uric acid | 140-420 µmol/L |
Leukocytes | 4.1-10.2x109/L | Creatinine | 40-110 µmol/L |
Thrombocytes | 150-400x109/L | Total bilirubin | to 20 µmol/L |
Total proteins | 60-80 g/L | Conjugated bilirubin | to 5 µmol/L |
Sodium | 132-145 mmol/L | Triglycerides | 0.7-1.9 mmol/L |
Potassium | 3.8-5.2 mmol/L | Total cholesterol | 3.8-5.2 mmol/L |
Chlorides | 97-108 mmol/L | HDL-cholesterol | F ˃ 1.6 mmol/L M ˃ 1.4 mmol/L |
Calcium | 2.25-2.75 mmol/L | LDL-cholesterol | < 3.4 mmol/L |
Glycemia | 3.3-5.6 mmol/L | Glycated hemoglobin | < 4 mmol/L |
Iron | 14.3-26.0 µmol/L M 10.7-21.5 µmol/L F | Serum phosphates | 0.7-1.6 mmol/L |